diff --git a/apps/web/package.json b/apps/web/package.json
index 11b4713d83..e6e2e30891 100644
--- a/apps/web/package.json
+++ b/apps/web/package.json
@@ -104,7 +104,6 @@
         "sanitize-html": "2.17.3",
         "tar-js": "^0.3.0",
         "ua-parser-js": "1.0.40",
-        "uuid": "^13.0.0",
         "what-input": "^5.2.10"
     },
     "devDependencies": {
diff --git a/apps/web/src/components/views/dialogs/devtools/StickyEventState.tsx b/apps/web/src/components/views/dialogs/devtools/StickyEventState.tsx
index 159fbc113b..96bebd5953 100644
--- a/apps/web/src/components/views/dialogs/devtools/StickyEventState.tsx
+++ b/apps/web/src/components/views/dialogs/devtools/StickyEventState.tsx
@@ -9,7 +9,6 @@ import React, { type ChangeEvent, useContext, useEffect, useMemo, useState } fro
 import { Pill } from "@element-hq/web-shared-components";
 import { MatrixEvent, type IContent, RoomStickyEventsEvent } from "matrix-js-sdk/src/matrix";
 import { Alert, Form, SettingsToggleInput } from "@vector-im/compound-web";
-import { v4 as uuidv4 } from "uuid";
 
 import BaseTool, { DevtoolsContext, type IDevtoolsProps } from "./BaseTool.tsx";
 import { _t, _td, UserFriendlyError } from "../../../../languageHandler.tsx";
@@ -330,7 +329,7 @@ export const StickyEventEditor: React.FC<IEditorProps> = ({ mxEvent, onBack }) =
     const defaultContent = mxEvent
         ? stringify(mxEvent.getContent())
         : stringify({
-              msc4354_sticky_key: uuidv4(),
+              msc4354_sticky_key: window.crypto.randomUUID(),
           });
     return <EventEditor fieldDefs={fields} defaultContent={defaultContent} onSend={onSend} onBack={onBack} />;
 };
diff --git a/apps/web/src/stores/room-list-v3/section.ts b/apps/web/src/stores/room-list-v3/section.ts
index f11a028693..45258956fa 100644
--- a/apps/web/src/stores/room-list-v3/section.ts
+++ b/apps/web/src/stores/room-list-v3/section.ts
@@ -5,8 +5,6 @@
  * Please see LICENSE files in the repository root for full details.
  */
 
-import { v4 as uuidv4 } from "uuid";
-
 import { SettingLevel } from "../../settings/SettingLevel";
 import SettingsStore from "../../settings/SettingsStore";
 import Modal from "../../Modal";
@@ -43,7 +41,7 @@ export async function createSection(): Promise<boolean> {
     const [shouldCreateSection, sectionName] = await modal.finished;
     if (!shouldCreateSection || !sectionName) return false;
 
-    const tag = `element.io.section.${uuidv4()}`;
+    const tag = `element.io.section.${window.crypto.randomUUID()}`;
     const newSection: CustomSection = { tag, name: sectionName };
 
     // Save the new section data
diff --git a/apps/web/src/utils/SessionLock.ts b/apps/web/src/utils/SessionLock.ts
index c93097aba1..afa18c2644 100644
--- a/apps/web/src/utils/SessionLock.ts
+++ b/apps/web/src/utils/SessionLock.ts
@@ -7,7 +7,6 @@ Please see LICENSE files in the repository root for full details.
 */
 
 import { logger } from "matrix-js-sdk/src/logger";
-import { v4 as uuidv4 } from "uuid";
 
 /*
  * Functionality for checking that only one instance is running at once
@@ -107,7 +106,7 @@ export function checkSessionLockFree(): boolean {
  */
 export async function getSessionLock(onNewInstance: () => Promise<void>): Promise<boolean> {
     /** unique ID for this session */
-    const sessionIdentifier = uuidv4();
+    const sessionIdentifier = window.crypto.randomUUID();
 
     const prefixedLogger = logger.getChild(`getSessionLock[${sessionIdentifier}]`);
 
diff --git a/apps/web/test/unit-tests/utils/SessionLock-test.ts b/apps/web/test/unit-tests/utils/SessionLock-test.ts
index 67202c7193..b0125debc5 100644
--- a/apps/web/test/unit-tests/utils/SessionLock-test.ts
+++ b/apps/web/test/unit-tests/utils/SessionLock-test.ts
@@ -253,8 +253,6 @@ describe("SessionLock", () => {
 
         // import the dependencies of getSessionLock into the new context
         // eslint-disable-next-line @typescript-eslint/no-require-imports
-        window2._uuid = require("uuid");
-        // eslint-disable-next-line @typescript-eslint/no-require-imports
         window2._logger = require("matrix-js-sdk/src/logger");
         window2.SESSION_LOCK_CONSTANTS = SESSION_LOCK_CONSTANTS;
 
diff --git a/pnpm-lock.yaml b/pnpm-lock.yaml
index f7c7cb59b1..87fe5912db 100644
--- a/pnpm-lock.yaml
+++ b/pnpm-lock.yaml
@@ -509,9 +509,6 @@ importers:
       ua-parser-js:
         specifier: 1.0.40
         version: 1.0.40
-      uuid:
-        specifier: ^13.0.0
-        version: 13.0.0
       what-input:
         specifier: ^5.2.10
         version: 5.2.12